Is a revolutionary method in molecular testing in which by just taking a blood sample from your arm (liquid biopsy) traces of circulating tumor DNA (ctDNA) in the bloodstream can be detected and distinguished from normal cell free DNA (cfDNA).
Because ctDNA is coming directly from a tumor site or from circulating tumor cells, therefore detecting traces of ctDNA in the bloodstream is a highly indicator of a potential tumor.
There are three types of genomic alterations that can be detected through liquid biopsy: base substitutions, indels, and rearrangements.
Liquid biopsy is very useful in cancer patients who are undergoing treatment since tumor progression can be monitored at specific time points during treatment.
Liquid biopsy is also making its way through early cancer detection as a screening tool for a variety of cancers such as lung, breast, ovarian, colon, leukemia and pancreatic cancer.